Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma

Published in communications medicine , 2022

This project explored tumor heterogeneity in a liver carcinoma adjacent to a benign lesion (focal nodular hyperplasia). Spatial genomic analysis revealed a clonal relationship between the lesions, providing the first genomic evidence of malignant transformation from a lesion previously considered benign.

Recommended citation: Ercan, Caner, et al. "Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report." Communications medicine 2.1 (2022): 11.
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